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Atrioventricular Block Secondary to Bortezomib Use in Multiple
Myeloma
A
Case of Disseminated and Fulminant Plasmacytomas That Developed
during Bortezomib Treatment
Like every drug, bortezomib has potential side effects and they
differ in nature and intensity in different patients.
The following side effects occur in greater than 30% of patients
who have taken bortezomib for treatmet of cancer. Most are similar
to the side effects of other chemotherapy agents.
- Fatigue
- Peripheral neuropathy: characterized by decreased sensation
and paresthesia (numbness and tingling of the hands and feet).
- Nausea and vomiting
- Diarrhea
- Poor appetite
- Constipation
- Low platelet count
- Fever
- Anemia
Less common side effects are arthralgia (joint pain) headache,
insomnia, edema (swelling of body parts), muscle pain, and low
white blood cell count. (This can put you at increased risk for
infection.)
Blood tests of patients have found lower than normal concentrations
of electrolytes such as sodium, potassium, magnesium, and calcium.
Patients have also reported:
- Shortness of breath
- Dizziness
- Dehydration
- Upper respiratory tract infection
- Cough
- Bone pain
- Anxiety
- Heartburn
- Abdominal pain
- Itching
- Blurring of visiom
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Bortezomib
What Is Bortezomib?